https://ethernia.org/research/Curated longevity research, evidence and frontier developments.enhttps://ethernia.org/research/#pig-kidney-bridgehttps://ethernia.org/research/#pig-kidney-bridgeA first-in-human report described porcine kidney transplantation followed later by a human transplant. One recipient spent 271 days free from dialysis with the pig kidney before declining graft function led to removal. Limit: Durable replacement for all recipients, freedom from immunosuppression, or whole-body rejuvenation.Thu, 03 Sep 2026 12:00:00 +0000https://ethernia.org/research/#er100-firsthttps://ethernia.org/research/#er100-firstThe sponsor reported the first patient dosed in the ER-100 eye study. A human safety study began dosing; this announcement contained no efficacy result. Limit: Restored vision, systemic age reversal or longer life.Tue, 09 Jun 2026 12:00:00 +0000https://ethernia.org/research/#galleri-primaryhttps://ethernia.org/research/#galleri-primaryGRAIL presented NHS-Galleri results at ASCO. The trial missed its primary endpoint; the sponsor also reported favourable stage-IV findings. Limit: A demonstrated cancer-mortality reduction.Sat, 30 May 2026 12:00:00 +0000https://ethernia.org/research/#rapa-exhttps://ethernia.org/research/#rapa-exRAPA-EX-01 tested weekly sirolimus alongside exercise. The primary chair-stand comparison did not establish an added benefit. Limit: That every rapamycin regimen is ineffective—or that a longevity benefit exists.Wed, 15 Apr 2026 12:00:00 +0000https://ethernia.org/research/#rapa-programmehttps://ethernia.org/research/#rapa-programmeUT Health San Antonio announced a trial programme in older adults. A research plan, not a treatment effect. Limit: Successful prevention of disability or longer survival.Mon, 16 Mar 2026 12:00:00 +0000https://ethernia.org/research/#ua-immunehttps://ethernia.org/research/#ua-immuneA short urolithin A trial reported changes in immune-cell measures. Biological activity in humans at the studied exposure. Limit: Fewer infections or extended survival.Fri, 31 Oct 2025 12:00:00 +0000https://ethernia.org/research/#engineered-cellshttps://ethernia.org/research/#engineered-cellsA Cell paper tested senescence-resistant human mesenchymal progenitor cells in aged primates. Ageing-related changes in a preclinical model. Limit: A demonstrated human rejuvenation therapy or human lifespan extension.Fri, 13 Jun 2025 12:00:00 +0000https://ethernia.org/research/#taurine-challengehttps://ethernia.org/research/#taurine-challengeA study challenged the assumption that circulating taurine consistently declines with age. The proposed universal biomarker relationship did not hold across the data examined. Limit: That every possible taurine intervention is ineffective.Thu, 05 Jun 2025 12:00:00 +0000https://ethernia.org/research/#ai-ipfhttps://ethernia.org/research/#ai-ipfRentosertib, a TNIK inhibitor, was tested in idiopathic pulmonary fibrosis. A small randomized disease-treatment trial reported early clinical findings. Limit: That AI has solved drug discovery or that the drug reverses human ageing.Tue, 03 Jun 2025 12:00:00 +0000https://ethernia.org/research/#pearlhttps://ethernia.org/research/#pearlA year-long rapamycin study reported its results. The primary visceral-fat outcome was not significant. Limit: General rejuvenation from exploratory subgroup findings.Fri, 04 Apr 2025 12:00:00 +0000https://ethernia.org/research/#fasting-programmehttps://ethernia.org/research/#fasting-programmeA 12-month trial compared intermittent and daily restriction with behavioural support. The intermittent programme produced greater weight loss. Limit: A fasting-specific slowing of ageing independent of calories and adherence.Tue, 01 Apr 2025 12:00:00 +0000